drugset / Trial / NCT00062023
Comparison of Sulindac, Aspirin, and Ursodiol in Preventing Colorectal Cancer
RandomizedSingle-groupSingle-blindPrevention
Summary
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. It is not yet known whether sulindac, aspirin, or ursodiol is more effective in preventing colorectal cancer. PURPOSE: This randomized phase II trial is studying how well sulindac works compared to aspirin or ursodiol in preventing colorectal cancer.
Timeline
- Start
- 2003-06
- Primary completion
- 2005-04
- Completion
- 2006-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aspirin | Small molecule | — | Oral |
| Comparator | Sulindac | Small molecule | — | Oral |
| Comparator | Ursodeoxycholic Acid | Small molecule | — | Oral |