drugset / Trial / NCT00074191

Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma

NCT00074191

Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as methotrexate, procarbazine, lomustine, dexamethasone, and cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients who have primary CNS lymphoma.

Timeline

Start
2000-01
Primary completion
2000-10
Completion
2000-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Cytarabine Small molecule Other
Subject Dexamethasone Small molecule Oral
Subject Lomustine Small molecule Oral
Subject Methotrexate Small molecule Intravenous
Subject procarbazine Small molecule Oral

Indications