drugset / Trial / NCT00094861

Study to Evaluate Palifermin in the Reduction of Dysphagia in Patients With Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

NCT00094861

Phase 2 Completed 100 enrolled Swedish Orphan Biovitrum Amgen · collab
RandomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine if palifermin will reduce the incidence of dysphagia in patients receiving concurrent chemoradiotherapy followed by consolidation chemotherapy for treatment of unresectable stage III Non-Small Cell Lung Cancer (NSCLC).

Timeline

Start
2005-01
Primary completion
2007-12
Completion
2014-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Palifermin Protein / enzyme biologic 180 ug/kg Intravenous
Background Carboplatin Small molecule Intravenous
Background Paclitaxel Small molecule 225 mg/m2 Intravenous