drugset / Trial / NCT00217295

A Safety Study of Combination Treatment With Avonex and Placebo-Controlled Dosing of Topamax in Relapsing-Remitting Multiple Sclerosis

NCT00217295

Phase 2 Unknown 30 enrolled Multiple Sclerosis Institute
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a clinical trial in relapsing-remitting Multiple Sclerosis to determine if Topamax added to Avonex has a neuroprotective effect as measured by the brain parenchymal fraction ( a measure of brain shrinkage) and by clinical assessment scores to evaluate disease progression.

Timeline

Start
2004-04
Primary completion
Completion
2007-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Topiramate Small molecule
Background Interferon beta-1a Protein / enzyme biologic

Indications