Acetylcholinesterase Inhibitors to Improve Cognitive Function and Overall Rehabilitation After a Stroke

Phase 4 Completed 40 enrolled University of Pittsburgh National Institute of Mental Health (NIMH) · collab

Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study will evaluate the effectiveness of treatment with acetylcholinesterase inhibitors in improving cognitive function and overall rehabilitation in elderly stroke survivors.

Timeline

Start: 2003-04
Primary completion: 2005-01
Completion: 2005-03

Publications

Results Whyte EM, Lenze EJ, Butters M, Skidmore E, Koenig K, Dew MA, Penrod L, Mulsant BH, Pollock BG, Cabacungan L, Reynolds CF 3rd, Munin MC. An open-label pilot study of acetylcholinesterase inhibitors to promote functional recovery in elderly cognitively impaired stroke patients. Cerebrovasc Dis. 2008;26(3):317-21. doi: 10.1159/000149580. Epub 2008 Jul 31.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Donepezil	Small molecule	10 mg	—
Subject	Galantamine	Small molecule	12 mg	—

Acetylcholinesterase Inhibitors to Improve Cognitive Function and Overall Rehabilitation After a Stroke

Summary

Timeline

Publications

Drugs

Indications