drugset / Trial / NCT00245089

Vincristine, Dactinomycin, and Cyclophosphamide in Treating Patients With Embryonal Rhabdomyosarcoma

NCT00245089

Phase 2 Unknown 41 enrolled Japan Rhabdomyosarcoma Study Group
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy, such as vincristine, dactinomycin, and cyclophosphamide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving vincristine, dactinomycin, and cyclophosphamide together works in treating patients with embryonal rhabdomyosarcoma.

Timeline

Start
2004-05
Primary completion
2011-04
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclophosphamide Other / unclassified Intravenous
Subject Dactinomycin Protein / enzyme biologic Intravenous
Subject Vincristine Small molecule Intravenous

Indications