drugset / Trial / NCT00281905

Combination Chemotherapy With or Without Radiation Therapy in Treating Children With Brain Tumors

NCT00281905 ↗

Phase 2 Unknown 50 enrolled Children's Cancer and Leukaemia Group
Open-labelTreatment

Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more tumor cells. Radiation therapy uses high-energy x-rays to kill tumor cells. Giving radiation therapy after chemotherapy may kill any remaining tumor cells. PURPOSE: This phase II trial is studying how well giving combination chemotherapy together with or without radiation therapy works in treating children with brain tumors.

Timeline

Start
1992-06
Primary completion
—
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Subject Carboplatin Small molecule — Intravenous
Subject Cisplatin Other / unclassified — Intravenous
Subject Cyclophosphamide Other / unclassified — Intravenous
Subject Methotrexate Small molecule — Intravenous
Subject Vincristine Small molecule — Intravenous