drugset / Trial / NCT00290823
Corticosteroids to Reduce Frequency of Seizures in Neurocysticercosis Patients
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether a short course of increased corticosteroid dosing with tapered dosing decreases seizure frequency as compared to standard corticosteroid dosing in patients with neurocysticercosis (NCC).
Timeline
- Start
- 2006-04
- Primary completion
- 2011-03
- Completion
- 2011-03
Publications
- Background Del Brutto OH. Neurocysticercosis. Semin Neurol. 2005 Sep;25(3):243-51. doi: 10.1055/s-2005-917661.
- Background Garcia HH, Gilman R, Martinez M, Tsang VC, Pilcher JB, Herrera G, Diaz F, Alvarado M, Miranda E. Cysticercosis as a major cause of epilepsy in Peru. The Cysticercosis Working Group in Peru (CWG). Lancet. 1993 Jan 23;341(8839):197-200. doi: 10.1016/0140-6736(93)90064-n.
- Background Medina MT, Rosas E, Rubio-Donnadieu F, Sotelo J. Neurocysticercosis as the main cause of late-onset epilepsy in Mexico. Arch Intern Med. 1990 Feb;150(2):325-7.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 6 mg | — |
| Subject | Dexamethasone | Small molecule | 8 mg | — |
| Background | Albendazole | Small molecule | 400 mg | Oral |
| Background | Omeprazole | Other / unclassified | 20 mg | Oral |