Use of Sugammadex at the End of Case in Routine Anesthesia (MK-8616-023)

Phase 3 Completed 224 enrolled Merck Sharp & Dohme LLC

NaSingle-groupOpen-labelTreatment

Summary

The primary purpose of the study is to determine the time-course of recovery to a T4/T1 ratio of 0.9 within 4 minutes after 4.0 mg.kg\^-1 Sugammadex is administered at least 15 minutes after the last administration of rocuronium in a wide range of surgical procedures and anesthetic regimens (routine use). Safety evaluation is part of the study.

Timeline

Start: 2005-10-27
Primary completion: 2006-05-22
Completion: 2006-05-22

Publications

Hudson ME, Rietbergen H, Chelly JE. Sugammadex is effective in reversing rocuronium in the presence of antibiotics. BMC Anesthesiol. 2014 Aug 15;14:69. doi: 10.1186/1471-2253-14-69. eCollection 2014.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sugammadex	Other / unclassified	4 mg/kg	Intravenous
Background	Rocuronium	Other / unclassified	0.15 mg/kg	Intravenous

Indications

No indication recorded.