drugset / Trial / NCT00364988

Pioglitazone and Losartan Provides Additional Renoprotection

NCT00364988

RandomizedParallel-groupOpen-labelTreatment

Summary

Peroxisomal proliferator-activated receptor agonist pioglitazone and rosiglitazone are currently used in the treatment of type 2 diabetes, as efficient insulin sensitizers alone or in combination with insulin.angiotensin II receptor antagonist losartan reduced the levels of proteinuria.Whether Combination therapy with pioglitazone and losartan provides additional renoprotection in subjects with type 2 diabetic nephropathy,it's worth researching.

Timeline

Start
2005-01
Primary completion
2005-12
Completion
2006-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Pioglitazone Small molecule 30 mg
Background Losartan Other / unclassified 100 mg