drugset / Trial / NCT00371306
Comparison of Glucovance to Insulin for Diabetes During Pregnancy
RandomizedSingle-groupSingle-blindTreatment
Summary
Pregnant women with gestational or Type 2 diabetes who require medication are placed in one of two groups: Insulin injections or Glucovance (oral administration). Blood glucose is checked 5 times per day, and medication adjusted by perinatologist according to glucose levels. The hypothesis is that patients will have similar or improved blood glucose control on an oral agent as compared to control on insulin.
Timeline
- Start
- 2002-09
- Primary completion
- —
- Completion
- 2008-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Glyburide | Small molecule | 1.25 mg | Oral |
| Subject | Glyburide | Small molecule | 5 mg | Oral |
| Subject | Insulin | Protein / enzyme biologic | 1 iu/kg | Other |
| Subject | Metformin | Small molecule | 250 mg | Oral |
| Subject | Metformin | Small molecule | 500 mg | Oral |