drugset / Trial / NCT00378547
Effect of Paracetamol, Pregabalin and Dexamethasone on Pain and Opioid Requirements in Patients Having a Tonsillectomy
RandomizedParallel-groupQuadruple-blindTreatment
Summary
Patients scheduled for a tonsillectomy need postoperative pain treatment. Some of the most widely used postoperative analgetics (NSAIDs) sometimes cause rebleeding in the postoperative period, and another often used analgetic, morphine, causes nausea and vomiting. The researchers therefore will investigate new combinations of postoperative analgesics in hopes of improving pain and the need for opioids during the postoperative period.
Timeline
- Start
- 2006-01
- Primary completion
- 2009-12
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Acetaminophen | Small molecule | 1 g | Oral |
| Subject | Dexamethasone | Small molecule | 8 mg | Intravenous |
| Subject | Pregabalin | Small molecule | 300 mg | Oral |
Indications
No indication recorded.