drugset / Trial / NCT00452907
ACT MALI: Treatment of Malaria Based on Combination Therapies
RandomizedParallel-groupOpen-labelTreatment
Summary
Test the hypothesis that repeated administration of Artesunate/Amiodaquine, Artesunate/Sulfadoxine-Pyrimethamine and Arthemeter-Lufemantrine for the treatment of consecutive episodes of uncomplicated malaria reduces the incidence of uncomplicated falciparum malaria and malaria attributable anemia
Timeline
- Start
- 2005-07
- Primary completion
- 2007-06
- Completion
- 2007-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Artesunate | Small molecule | 50 mg | Oral |
| Comparator | Sulfadoxine-pyrimethamine | Small molecule | 500 mg | Oral |
| Comparator | arthemether | Unknown | 20 mg | Oral |
| Comparator | lumefantrine | Small molecule | 120 mg | Oral |
| Comparator | pyrimethamine | Small molecule | 25 mg | Oral |