drugset / Trial / NCT00479752
Safety and Efficacy of Folfox4 + Weekly Cetuximab vs Folfox 4+Biweekly Cetuximab by Metastatic Colorectal Cancer
RandomizedParallel-groupOpen-labelTreatment
Summary
To assess the efficacy of FOLFOX4 in combination with cetuximab, weekly and FOLFOX4 in combination with cetuximab, biweekly.
Timeline
- Start
- 2008-01
- Primary completion
- 2010-06
- Completion
- 2015-11
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Cetuximab | Monoclonal antibody | 250 mg/m2 | — |
| Comparator | Cetuximab | Monoclonal antibody | 500 mg/m2 | — |
| Comparator | Leucovorin | Small molecule | 200 mg/m2 | — |
| Comparator | Oxaliplatin | Small molecule | 85 mg/m2 | — |
| Comparator | fluorouracil | Small molecule | 400 mg/m2 | — |
| Comparator | fluorouracil | Small molecule | 600 mg/m2 | — |