drugset / Trial / NCT00481182
Co-Administration Of Fosamprenavir With Methadone: A Drug Interaction Study.
Non-randomizedSingle-groupOpen-labelTreatment
Summary
To assess the combined effects of fosamprenavir 700mg BID + ritonavir 100mg BID + standardized dose of methadone, on plasma total and unbound methadone enantiomer pharmacokinetics (PK), opiate pharmacodynamic (PD) measures, and safety. The effect of methadone on plasma amprenavir PK will also be assessed by comparison to historical control data.
Timeline
- Start
- 2005-02
- Primary completion
- —
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fosamprenavir | Small molecule | 700 mg | — |
| Subject | Methadone | Other / unclassified | — | — |
| Background | Ritonavir | Other / unclassified | 100 mg | — |
Indications
No indication recorded.