drugset / Trial / NCT00487110

Clinical Confirmation of a Pharmacodynamic Interaction Between Tropisetron and Paracetamol

NCT00487110

Phase 4 Completed 40 enrolled University Hospital, Clermont-Ferrand
RandomizedParallel-groupDouble-blindTreatment

Summary

A previous study has shown that tropisetron inhibits the analgesic effect of paracetamol in healthy volunteers. This study aims at confirming this pharmacodynamic interaction in patients with post-surgery pain.

Timeline

Start
2008-06
Primary completion
2008-12
Completion
2009-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Acetaminophen Small molecule
Subject Tropisetron Small molecule

Indications

No indication recorded.