drugset / Trial / NCT00506194
Short-Term Intensive Insulin Therapy Induction of Long-term Glycemic Control
RandomizedParallel-groupOpen-labelTreatment
Summary
We designed this prospective, randomized control study to compare the benefits between the insulin therapy and OADs after correction of the glucose toxicity with a short period of intensive insulin therapy.
Timeline
- Start
- 2005-10
- Primary completion
- 2007-08
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Gliclazide MR | Small molecule | 30 mg | Oral |
| Comparator | Gliclazide MR | Small molecule | 60 mg | Oral |
| Subject | Insulatard | Protein / enzyme biologic | 75 % | — |
| Comparator | Metformin | Small molecule | 250 mg | Oral |
| Comparator | Glimepiride | Small molecule | — | Oral |
| Background | INSULIN HUMAN ZINC | Protein / enzyme biologic | — | — |
| Background | insulin glargine | Protein / enzyme biologic | — | — |
| Background | regular insulin | Protein / enzyme biologic | — | — |