drugset / Trial / NCT00513578

Vaccine Therapy and GM-CSF in Treating Patients With Low-Risk or Intermediate-Risk Myelodysplastic Syndrome

NCT00513578

Phase 2 Unknown 30 enrolled The Vaccine Company
Open-labelTreatment

Summary

RATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill cancer cells. Colony-stimulating factors, such as GM-CSF, increase the number of white blood cells and platelets found in bone marrow or peripheral blood. Giving vaccine therapy together with GM-CSF may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving vaccine therapy together with GM-CSF works in treating patients with low-risk or intermediate-risk myelodysplastic syndrome.

Timeline

Start
2007-01
Primary completion
2009-01
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject TVC-PR1 Vaccine Subcutaneous
Background incomplete Freund's adjuvant Other / unclassified Subcutaneous
Background sargramostim Protein / enzyme biologic