drugset / Trial / NCT00531999

Raltegravir Insulin Sensitivity Study

NCT00531999

Phase 1 Completed 18 enrolled St Stephens Aids Trust
RandomizedParallel-groupOpen-label

Summary

The purpose of the study is to look at the effects of two different HIV medications on the body's response to insulin (a hormone that regulates blood sugar levels). This will be done using a method called the 'euglycaemic clamp' The study will also investigate the effects of these drugs on blood fats and on circulating markers in the blood stream related to blood vessels (vascular inflammation markers).

Timeline

Start
2007-10
Primary completion
2008-08
Completion
2008-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lopinavir Other / unclassified 400 mg
Comparator Raltegravir Other / unclassified 400 mg
Comparator Ritonavir Other / unclassified 100 mg