drugset / Trial / NCT00559481
Ketoconazole, Dexamethasone, and Hydrocortisone in Treating Patients With Prostate Cancer That Did Not Respond to Androgen-Deprivation Therapy
RandomizedOpen-labelTreatment
Summary
RATIONALE: Studying samples of blood in the laboratory from patients with cancer receiving ketoconazole together with dexamethasone and hydrocortisone may help doctors learn more about how these drugs are used by the body. PURPOSE: This randomized clinical trial is studying how ketoconazole, dexamethasone, and hydrocortisone act in the body of patients with prostate cancer that did not respond to androgen-deprivation therapy.
Timeline
- Start
- 2007-10
- Primary completion
- 2008-09
- Completion
- —
Outcome
Outcome not reported
Stopped (Enrollment): “Withdrawn due to low accrual”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | — | Oral |
| Subject | Hydrocortisone | Other / unclassified | — | Oral |
| Background | Ketoconazole | Small molecule | — | Oral |