Epidural Clonidine for Lumbosacral Radiculopathy

Terminated 26 enrolled Mayo Clinic National Center for Research Resources (NCRR) · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This was a randomized, blinded study of transforaminal epidural injection of clonidine versus a similar injection of corticosteroid for acute lumbosacral radiculopathy. The hypothesis was that clonidine will be as effective as steroid for this condition.

Timeline

Start: 2006-10
Primary completion: 2009-02
Completion: 2009-02

Publications

Results Burgher AH, Hoelzer BC, Schroeder DR, Wilson GA, Huntoon MA. Transforaminal epidural clonidine versus corticosteroid for acute lumbosacral radiculopathy due to intervertebral disc herniation. Spine (Phila Pa 1976). 2011 Mar 1;36(5):E293-300. doi: 10.1097/BRS.0b013e3181ddd597.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Clonidine	Other / unclassified	0.2 mg	Other
Subject	Clonidine	Other / unclassified	0.4 mg	Other
Comparator	Triamcinolone Hexacetonide	Other / unclassified	40 mg	Other
Comparator	Triamcinolone Hexacetonide	Other / unclassified	80 mg	Other
Background	Lidocaine	Other / unclassified	1 ml	Other

Epidural Clonidine for Lumbosacral Radiculopathy

Summary

Timeline

Publications

Drugs

Indications