drugset / Trial / NCT00640822

Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment Compared With Tacalcitol Ointment in Patients With Psoriasis on the Face and Skin Folds

NCT00640822

Phase 3 Completed 782 enrolled LEO Pharma
RandomizedParallel-groupSingle-blindTreatment

Summary

There are few therapies suitable for the treatment of psoriasis on the face and skin folds. As these areas are sensitive, irritation and other adverse reactions are more common than elsewhere on the body. The purpose of the study is to compare the efficacy and safety of once daily treatment for up to 8 weeks of an ointment containing calcipotriol 25 mcg/g plus hydrocortisone 10 mg/g with tacalcitol 4 mcg/g ointment and the ointment vehicle alone in patients with psoriasis vulgaris on the face and on the intertriginous ares

Timeline

Start
2008-02
Primary completion
2009-06
Completion
2009-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Calcipotriol Small molecule 25 unknown Topical
Subject Hydrocortisone Other / unclassified 10 unknown Topical
Comparator Tacalcitol Small molecule 4 unknown Topical

Indications