Local Infiltration Analgesia Following Unicompartmental Knee Arthroplasty

Completed 40 enrolled Region Örebro County

RandomizedParallel-groupQuadruple-blindTreatment

Summary

The primary aim of this study is to evaluate if intra- and postoperative administration of ropivacaine, ketorolac and epinephrine into the operating field would affect hospital stay. Secondary end-points are morphine consumption, pain intensity and side effects. In an attempt to assess the safety of this technique, knee function and patient satisfaction scores are assessed up to 6 months after surgery.

Timeline

Start: 2005-09
Primary completion: 2007-03
Completion: 2007-09

Publications

Essving P, Axelsson K, Kjellberg J, Wallgren O, Gupta A, Lundin A. Reduced hospital stay, morphine consumption, and pain intensity with local infiltration analgesia after unicompartmental knee arthroplasty. Acta Orthop. 2009 Apr;80(2):213-9. doi: 10.3109/17453670902930008.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Epinephrine	Other / unclassified	0.1 mg	Other
Comparator	Ketorolac	Other / unclassified	30 mg	Other
Comparator	Ropivacaine	Other / unclassified	150 mg	Other

Indications

No indication recorded.