drugset / Trial / NCT00659945
Aprepitant for PONV Prophylaxis in Outpatient Plastic Surgery
RandomizedParallel-groupDouble-blindPrevention
Summary
Hypothesis: Aprepitant plus ondansetron is more effective than ondansetron plus placebo for prevention of postoperative emesis in patients at moderate-to-high risk for PONV for up to 48 hours after surgery. Specific Aim: To determine the incidence of PONV during the first 48 hours after surgery; in patients who have received aprepitant plus ondansetron versus ondansetron plus placebo for up to 48 hours after surgery.
Timeline
- Start
- 2008-06
- Primary completion
- 2009-11
- Completion
- 2010-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Aprepitant | Other / unclassified | — | — |
| Comparator | Ondansetron | Other / unclassified | 4 mg | Intravenous |
Indications
No indication recorded.