drugset / Trial / NCT00706771
Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The investigators will determine the feasibility, safety and efficacy of intravenous sodium bicarbonate in reducing progression to overt acute renal failure in patients with the systemic inflammatory response syndrome, and low urine output or early acute renal impairment as defined by serum neutrophil gelatinase-associated lipocalin (NGAL).
Timeline
- Start
- 2010-02
- Primary completion
- 2012-09
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | sodium bicarbonate | Diagnostic / imaging agent | 0.2 unknown | Intravenous |
| Comparator | sodium chloride | Unknown | 0.2 unknown | — |