drugset / Trial / NCT00706771

Bicarbonate and Lipocalin in Systemic Inflammatory Response Syndrome (SIRS) Study

NCT00706771

Phase 2 Completed 70 enrolled Austin Health
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The investigators will determine the feasibility, safety and efficacy of intravenous sodium bicarbonate in reducing progression to overt acute renal failure in patients with the systemic inflammatory response syndrome, and low urine output or early acute renal impairment as defined by serum neutrophil gelatinase-associated lipocalin (NGAL).

Timeline

Start
2010-02
Primary completion
2012-09
Completion
2012-09

Drugs

EvaluationDrugModalityDoseRoute
Comparator sodium bicarbonate Diagnostic / imaging agent 0.2 unknown Intravenous
Comparator sodium chloride Unknown 0.2 unknown