drugset / Trial / NCT00743509
A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma
Non-randomizedSingle-groupOpen-labelTreatment
Summary
The purpose of this Phase II study will assess the effectiveness of the combination of oral cyclophosphamide and sirolimus in sarcoma patients with relapsed or widespread disease who cannot be cured by surgery, radiation or conventional chemotherapy.
Timeline
- Start
- 2008-08
- Primary completion
- 2010-04
- Completion
- 2012-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Cyclophosphamide | Other / unclassified | 200 mg | Oral |
| Subject | Sirolimus | Small molecule | 4 mg | Oral |