drugset / Trial / NCT00744081

Imatinib + MTC in Relapsed / Refractory Acute Myeloid Leukemia (AML)

NCT00744081

Phase 2 Completed 130 enrolled Goethe University
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to show superiority in complete responses of combination therapy MTC plus Glivec in patients with refractory or relapsed AML compared to a historical control which was treated with MTC alone.

Timeline

Start
2004-07
Primary completion
2010-12
Completion
2010-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Imatinib Small molecule
Background Cytarabine Small molecule
Background Mitoxantrone Small molecule
Background Topotecan Small molecule