drugset / Trial / NCT00772499
Vascular Improvement With Olmesartan Medoxomil Study
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare in patients with primary hypertension, the non-blood pressure lowering effects of one-year therapy with olmesartan medoxomil vs. those of atenolol on changes in the vascular structure and function.
Timeline
- Start
- 2002-11
- Primary completion
- 2005-07
- Completion
- 2005-07
Outcome
Met primary endpoint
release “At the end of the study the W/L ratio in the olmesartan medoxomil-based treatment group was significantly reduced” daiichisankyo.com ↗
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Atenolol | Other / unclassified | — | Oral |
| Subject | Olmesartan medoxomil | Unknown | — | Oral |
| Comparator | Amlodipine | Other / unclassified | — | Oral |
| Comparator | Hydralazine | Small molecule | — | Oral |
| Comparator | Hydrochlorothiazide | Unknown | — | Oral |