drugset / Trial / NCT00781612

A Safety Extension Study of Trastuzumab Emtansine in Participants Previously Treated With Trastuzumab Emtansine Alone or in Combination With Other Anti-Cancer Therapy in One of the Parent Studies

NCT00781612

Phase 2 Active not recruiting 720 enrolled Genentech, Inc. Hoffmann-La Roche · collab
NaSingle-groupOpen-labelTreatment

Summary

This is a global, multicenter, open-label safety extension study. Participants receiving single-agent trastuzumab emtansine or trastuzumab emtansine administered in combination with other anti-cancer therapies in a Genentech / Roche-sponsored parent study who are active and receiving benefit at the closure of parent study are eligible for continued treatment in this study.

Timeline

Start
2008-10-16
Primary completion
2029-09-30
Completion
2030-04-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Trastuzumab emtansine Other / unclassified 3.6 mg/kg Intravenous
Background Atezolizumab Monoclonal antibody 1200 mg Intravenous
Background Docetaxel Small molecule
Background Paclitaxel Small molecule
Background Pertuzumab Monoclonal antibody 420 mg Intravenous
Background Trastuzumab Monoclonal antibody

Indications