drugset / Trial / NCT00800839
Busulfan and Fludarabine Followed by Post-transplant Cyclophosphamide
NaSingle-groupOpen-labelTreatment
Summary
The goal of this clinical research study is to learn if cyclophosphamide given after busulfan and fludarabine can help to prevent graft versus host disease (GVHD - a condition in which transplanted tissue attacks the body into which it is transplanted) in patients receiving a stem cell transplant. The safety of this drug combination will also be studied.
Timeline
- Start
- 2008-09
- Primary completion
- 2015-07
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Busulfan | Small molecule | 32 mg/m2 | Intravenous |
| Subject | Cyclophosphamide | Other / unclassified | 50 mg/kg | Intravenous |
| Subject | Fludarabine | Small molecule | 40 mg/m2 | Intravenous |