drugset / Trial / NCT00805311
Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis
RandomizedParallel-groupOpen-labelPrevention
Summary
The aim of this study is to determine whether optimal medical treatment can postpone carotid endarterectomy.
Timeline
- Start
- 2009-04
- Primary completion
- 2014-05
- Completion
- 2014-05
Publications
- Background Kolos I, Troitskiy A, Balakhonova T, Shariya M, Skrypnik D, Tvorogova T, Deev A, Boytsov S; Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) Study Group. Modern medical treatment with or without carotid endarterectomy for severe asymptomatic carotid atherosclerosis. J Vasc Surg. 2015 Oct;62(4):914-22. doi: 10.1016/j.jvs.2015.05.005.
- Results Kolos I, Loukianov M, Dupik N, Boytsov S, Deev A. Optimal medical treatment versus carotid endarterectomy: the rationale and design of the Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) study. Int J Stroke. 2015 Feb;10(2):269-74. doi: 10.1111/ijs.12019. Epub 2013 Mar 15.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Background | Amlodipine | Other / unclassified | 5 mg | — |
| Background | Aspirin | Small molecule | 100 mg | — |
| Background | Atorvastatin | Small molecule | 10 mg | — |
| Background | Losartan | Other / unclassified | 50 mg | — |