drugset

drugset / Trial / NCT00809718

The Effect of Rifapentine on Raltegravir

NCT00809718 ↗

Phase 1 Completed 27 enrolled The University of Texas Health Science Center at San Antonio Centers for Disease Control and Prevention · collab Merck Sharp & Dohme LLC · collab VA Office of Research and Development · collab

NaSingle-groupOpen-label

Summary

The aim of this study is to study the effect of rifapentine on plasma concentrations of raltegravir.

Timeline

Start: 2009-02
Primary completion: 2011-05
Completion: 2011-08

Publications

Weiner M, Egelund EF, Engle M, Kiser M, Prihoda TJ, Gelfond JA, Mac Kenzie W, Peloquin CA. Pharmacokinetic interaction of rifapentine and raltegravir in healthy volunteers. J Antimicrob Chemother. 2014 Apr;69(4):1079-85. doi: 10.1093/jac/dkt483. Epub 2013 Dec 15.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Raltegravir	Other / unclassified	400 mg	Oral
Subject	Rifapentine	Small molecule	600 mg	Oral
Subject	Rifapentine	Small molecule	900 mg	Oral

Indications

No indication recorded.