drugset / Trial / NCT00835965
Oral Aprepitant and Lower Dose Dexamethasone Versus Aprepitant Alone for Preventing Postoperative Nausea and Vomiting (PONV) After Elective Laparoscopic Surgeries
Unknown
50 enrolled
Main Line Health
Drexel University College of Medicine · collabMerck Sharp & Dohme LLC · collab
RandomizedParallel-groupDouble-blindPrevention
Summary
The combination of aprepitant and lower dose dexamethasone is superior to aprepitant alone with respect to the proportion of patients with a complete response (no vomiting and no use of rescue therapy) during 24 hours after the placement of last suture/staple.
Timeline
- Start
- 2009-02
- Primary completion
- 2009-12
- Completion
- —
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Dexamethasone | Small molecule | 5 mg | Intravenous |
| Comparator | Aprepitant | Other / unclassified | 40 mg | Oral |
Indications
No indication recorded.