drugset / Trial / NCT00867152
GSK1349572 Drug Interaction With Etravirine and Either Darunavir/Ritonavir or Lopinavir/Ritonavir
RandomizedParallel-groupOpen-labelBasic science
Summary
A Phase I, open label, randomized, three period, one-way, two cohort, adaptive crossover study to evaluate the effect of darunavir/ritonavir plus etravirine and lopinavir/ritonavir plus etravirine on GSK1349572 pharmacokinetics in healthy adult subjects
Timeline
- Start
- 2009-04
- Primary completion
- 2009-05
- Completion
- 2009-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Darunavir | Small molecule | 600 mg | — |
| Subject | Dolutegravir | Other / unclassified | 20 mg | — |
| Subject | Dolutegravir | Other / unclassified | 50 mg | — |
| Subject | Lopinavir | Other / unclassified | 400 mg | — |
| Background | Etravirine | Small molecule | 200 mg | — |
| Background | Ritonavir | Other / unclassified | 100 mg | — |
Indications
No indication recorded.