drugset / Trial / NCT00885495
Darunavir/Ritonavir and Rosuvastatin Pharmacokinetic Study
RandomizedCrossoverOpen-labelTreatment
Summary
This is a phase I, open-label, controlled drug interaction study to determine the effects of darunavir plus ritonavir on the pharmacokinetics of the hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, rosuvastatin, in HIV-1-seronegative subjects.
Timeline
- Start
- 2009-01
- Primary completion
- 2010-04
- Completion
- 2010-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Darunavir | Small molecule | 600 mg | — |
| Comparator | Ritonavir | Other / unclassified | 100 mg | — |
| Comparator | Rosuvastatin | Small molecule | 10 mg | — |