drugset / Trial / NCT00959647

A Study of Vismodegib (GDC-0449) in Patients Treated With Vismodegib in a Previous Genentech-sponsored Phase I or II Cancer Study

NCT00959647

Phase 2 Completed 19 enrolled Genentech, Inc.
NaSingle-groupOpen-labelTreatment

Summary

This was a multicenter, open-label extension study. Patients who received vismodegib (GDC-0449) in a Genentech-sponsored study and who had completed the parent study or who continued to receive vismodegib at the time the parent study closed were eligible for continued treatment in this protocol.

Timeline

Start
2009-09-03
Primary completion
2014-01-09
Completion
2014-01-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Vismodegib Small molecule 150 mg Oral
Background Bevacizumab Monoclonal antibody Intravenous
Background Irinotecan Small molecule Intravenous
Background Leucovorin Small molecule Intravenous
Background Oxaliplatin Small molecule Intravenous
Background fluorouracil Small molecule Intravenous