A Study to Compare Patient-controlled Pain Medications Delivered Either Through the Skin or Intravenously

Phase 4 Completed 657 enrolled Janssen-Cilag International NV Alza Corporation, DE, USA · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the effectiveness and safety of a patient-controlled system to deliver fentanyl compared with a patient-controlled intravenous system to deliver morphine in the management of postoperative pain.

Timeline

Start: 2004-06
Primary completion: 2005-04
Completion: 2005-04

Publications

Results Grond S, Hall J, Spacek A, Hoppenbrouwers M, Richarz U, Bonnet F. Iontophoretic transdermal system using fentanyl compared with patient-controlled intravenous analgesia using morphine for postoperative pain management. Br J Anaesth. 2007 Jun;98(6):806-15. doi: 10.1093/bja/aem102.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Fentanyl	Other / unclassified	40 ug	Other
Comparator	Morphine	Other / unclassified	20 mg	Intravenous

Indications

No indication recorded.