drugset / Trial / NCT01005290
A Pharmacodynamic Study to Evaluate the Effect of a Fixed Dose Combination Pill on Blood Pressure
RandomizedCrossoverOpen-label
Summary
The purpose of this study is to compare the effect on systolic pressure of the 3 drugs given together in the cardiovascular combination pill (acetylsalicylic acid, simvastatin, and ramipril) to the effect on systolic pressure of ramipril given alone.
Timeline
- Start
- 2009-10
- Primary completion
- 2010-10
- Completion
- 2010-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Aspirin | Small molecule | 100 mg | Oral |
| Comparator | Ramipril | Small molecule | 10 mg | Oral |
| Subject | Simvastatin | Small molecule | 40 mg | Oral |