drugset / Trial / NCT01009944

Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study

NCT01009944

NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to develop an approach to provide personalized medicine to individuals who have hypertension (high blood pressure). The investigators plan to use people's genetic characteristics (traits) to determine what medication they should use to lower their blood pressure most effectively. The investigators will give individuals one of two medications to treat hypertension (lisinopril or atenolol). The investigators believe that depending on the individuals genetic background one medication will work better in lowering their blood pressure.

Timeline

Start
2007-01
Primary completion
2019-03-19
Completion
2019-03-19

Drugs

EvaluationDrugModalityDoseRoute
Subject Atenolol Other / unclassified
Subject LISINOPRIL ANHYDROUS Small molecule

Indications