drugset / Trial / NCT01020539

Allogeneic Stem Cell Transplantation Followed By Targeted Immune Therapy In Average Risk Leukemia

NCT01020539

Phase 1 Completed 18 enrolled Columbia University
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Allogeneic stem cell transplantation (AlloSCT) followed by targeted immune therapy Gemtuzumab Ozogamicin patients with acute myeloid leukemia (AML)/juvenile myelomonocytic leukemia (JMML)/myelodysplastic syndromes (MDS) will be safe and well tolerated.

Timeline

Start
2002-09-11
Primary completion
2011-07-20
Completion
2020-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemtuzumab Ozogamicin Monoclonal antibody
Background ANTILYMPHOCYTE IMMUNOGLOBULIN (HORSE) Protein / enzyme biologic
Background Busulfan Small molecule
Background Fludarabine Small molecule
Background Isotretinoin Other / unclassified
Background Methotrexate Small molecule
Background Mycophenolate Mofetil Small molecule
Background Tacrolimus Small molecule