drugset / Trial / NCT01036594
Ketoconazole and Dexamethasone in Prostate Cancer
Non-randomizedSequentialOpen-labelTreatment
Summary
This is an open label, phase II, single center trial of ketoconazole/dexamethasone to determine if the administration of ketoconazole/dexamethasone, after disease progression with ketoconazole/hydrocortisone slows or reverses disease progression in men with progressive prostate cancer.
Timeline
- Start
- 2009-12-11
- Primary completion
- 2012-12-11
- Completion
- 2014-10-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Dexamethasone | Small molecule | 0.5 mg | Oral |
| Subject | Hydrocortisone | Other / unclassified | 10 mg | Oral |
| Subject | Hydrocortisone | Other / unclassified | 20 mg | Oral |
| Subject | Ketoconazole | Small molecule | 400 mg | Oral |