drugset / Trial / NCT01060774
Bupivacaine Versus Lidocaine on Inflammatory Regulation
RandomizedParallel-groupTriple-blindOther
Summary
This study is testing a local anesthetic (numbing medicine) to suppress pain. Bupivacaine and lidocaine are FDA approved local anesthetics that may decrease pain following surgery. Patients will receive either 2% lidocaine, 0.5% bupivacaine, or placebo with epinephrine 1:200,000 as a numbing medicine at the end of root canal surgery. Small pieces of gum will be taken before and after surgery and 2 days later to analyze chemicals that may be related to pain sensation.
Timeline
- Start
- 2008-07
- Primary completion
- 2009-07
- Completion
- 2010-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Bupivacaine | Other / unclassified | 0.5 % | — |
| Subject | Lidocaine | Other / unclassified | 2 % | — |
Indications
No indication recorded.