drugset / Trial / NCT01061853
Efficacy of Topical Rapamycin to Treat Chronic Erosive Oral Lichen
Phase 3
Terminated
76 enrolled
University Hospital, Tours
Institut National de la Santé Et de la Recherche Médicale, France · collab
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to determine wether topical rapamycin is more efficient than topical steroids in the treatment of chronic erosive lichen planus.
Timeline
- Start
- 2008-02
- Primary completion
- 2012-11
- Completion
- 2012-11
Outcome
Outcome not reported
Stopped (Enrollment): “Per protocol intermediate analyses of 76 patients and enrollment difficulties.”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Betamethasone | Other / unclassified | 0.05 % | Topical |
| Subject | Sirolimus | Small molecule | 1 mg/ml | Topical |