drugset / Trial / NCT01063439

BuEAM Conditioning for Autologous Stem Cell Transplantation (ASCT) to Treat Diffuse Large B Cell Lymphoma (DLCBL)

NCT01063439 ↗

Phase 2 Unknown 42 enrolled Inje University
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the efficacy and toxicity of busulfan, etoposide, cytarabine and melphalan (BuEAM) including intravenous busulfan instead of BCNU of standard BEAM as a conditioning for autologous stem cell transplantation in patients with NHL.

Timeline

Start
2010-01
Primary completion
2014-08
Completion
2015-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Busulfan Small molecule 3.2 mg/kg Intravenous
Subject Cytarabine Small molecule 1 g —
Subject Etoposide Small molecule 400 mg/m2 —
Subject Melphalan Small molecule 140 mg/m2 —

Indications