drugset / Trial / NCT01068652

Effect of Different Insulin Administrations, All in Combination With Metformin, on Glycaemic Control in Subjects With Type 2 Diabetes Inadequately Controlled by Oral Anti-diabetic Drugs

NCT01068652

Phase 4 Completed 403 enrolled Novo Nordisk A/S
RandomizedParallel-groupOpen-labelTreatment

Summary

This trial is conducted in Africa. The aim of this clinical trial is to investigate the effect of 50 weeks of treatment with different intensified insulin administrations (all in combination with a fixed dose of metformin) on blood sugar control in subjects with type 2 diabetes inadequately controlled by oral anti-diabetic drugs (OADs).

Timeline

Start
2010-03
Primary completion
2012-05
Completion
2012-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator biphasic insulin aspart 30 Protein / enzyme biologic 0.1 iu/kg Subcutaneous
Comparator insulin aspart Protein / enzyme biologic Subcutaneous
Comparator insulin detemir Protein / enzyme biologic 0.1 iu/kg Subcutaneous
Comparator Metformin Small molecule 1000 mg
Comparator Metformin Small molecule 2000 mg