Atazanavir/Ritonavir and Darunavir/Ritonavir PK Tail Study

Summary

The purpose of the study is to look at the levels of three HIV medications darunavir, ritonavir and atazanavir in the blood after the drug intake has been stopped in order to understand how long these drugs persist in blood for. The study will specifically look at these three drugs blood levels after taking them for 10 days everyday. The main objective is to provide information on the potential safety (in terms of preventing virological failure and the development of resistance)of delaying drug doses occasionally by providing information on the decline in drug concentration after dosing has stopped.

Timeline

Start

2010-04

Primary completion

2010-06

Completion

2010-06

Drugs

Indications