drugset / Trial / NCT01101568
A Study to Investigate the Interaction of GSK1292263 With Rosuvastatin and Simvastatin in Healthy Subjects
Non-randomizedSingle-groupOpen-labelOther
Summary
This study is a Phase I, open-label, single-sequence drug interaction study to evaluate the effect of repeated doses of GSK1292263 on the pharmacokinetics of rosuvastatin and simvastatin in healthy adult subjects. Each subject will receive single doses of simvastatin and rosuvastatin on two occasions, once alone and once following administration of repeated (BID) doses of GSK1292263.
Timeline
- Start
- 2010-04-14
- Primary completion
- 2010-06-24
- Completion
- 2010-06-24
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | GSK1292263 | Small molecule | 300 mg | — |
| Subject | Rosuvastatin | Small molecule | 10 mg | — |
| Subject | Simvastatin | Small molecule | 40 mg | — |