drugset / Trial / NCT01189695
Maintenance Boosted Lopinavir Monotherapy Following Salvage Protease-inhibitor (PI) Based Regimen in HIV With Non-nucleoside Reverse Transcriptase Inhibitors (NNRTI) Based Regimen Failure
Phase 4
Completed
63 enrolled
Bamrasnaradura Infectious Diseases Institute
Department of Disease Control, Thailand · collab
RandomizedParallel-groupOpen-labelTreatment
Summary
The objective of this study is to determine efficacy of ritonavir-boosted lopinavir monotherapy as a maintenance regimen in HIV-1-infected patients who previously failed Non-nucleoside reverse transcriptase inhibitors (NNRTI) based regimens and currently received salvage protease-inhibitor (PI) based regimens.
Timeline
- Start
- 2010-12
- Primary completion
- 2012-12
- Completion
- 2013-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lopinavir | Other / unclassified | 200 mg | — |
| Comparator | Etravirine | Small molecule | — | — |
| Comparator | Raltegravir | Other / unclassified | — | — |
| Background | Ritonavir | Other / unclassified | 50 mg | — |