drugset / Trial / NCT01240928

MK-2206+Endocrine Therapy in Patients With Hormone Receptor-Positive Breast Cancer

NCT01240928

NaSingle-groupOpen-labelTreatment

Summary

This is a phase Ib trial that evaluates the safety and tolerability of MK-2206 given in combination with exemestane +/- goserelin in pre- and post-menopausal patients with hormone receptor-positive metastatic breast cancer.

Timeline

Start
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-2206 Small molecule 135 mg Oral
Background Exemestane Small molecule 25 mg Oral
Background Goserelin Other / unclassified 3.6 mg Subcutaneous

Indications