drugset / Trial / NCT01240941

Trial of MK-2206 + Endocrine Treatment in Patients With Hormone Receptor Positive Breast Cancer

NCT01240941

NaSingle-groupOpen-labelTreatment

Summary

This is a phase II Trial of MK-2206 in combination with Endocrine Therapy in patients with Hormone Receptor Breast Cancer. After the maximum tolerated dose is determined in the phase 1b trial (under a separate NCT number), efficacy will be evaluated among 17 patients.

Timeline

Start
2011-02
Primary completion
2012-06
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject MK-2206 Small molecule Oral
Background Exemestane Small molecule 25 mg Oral
Background Goserelin Other / unclassified 3.6 mg Oral

Indications